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A standard starting dose is 0.25 mg , which is one-quarter of a standard 1 mg dose

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Other than saroglitazar, elafibranor, a PPAR / agonist, was tested in a 1-year phase II RCT involving 274 subjects with biopsy-proven NASH, 107 of whom were diabetic: using a modified post hoc primary endpoint, elafibranor resolved NASH in a significant percentage of patients, without worsening of fibrosis, and ameliorated the hepatic and metabolic profile [67]

The secondary outcomes included comparing the proportion and duration of time spent in the target range at 24 and 52 weeks

You also need CoA for the transport of long chain fatty acids into mitochondria where fats are converted into energy