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JCI Insight 6, e145632
[Abstract]2026 Aug 1:251:229-242
Modelling Tools to Characterize Acetaminophen Pharmacokinetics in the Pregnant Population
Month 1: Women : 1.5 mg once weekly Men : 1.8 mg once weekly Month 2: Women: 3 mg once weekly (compared to the standard 5 mg) Men : 3.6 mg once weekly (compared to the standard 5 mg) Month 3: Women : 4.5 mg once weekly (instead of the standard 7.5 mg) Men : 5.4 mg once weekly (instead of the standard 7.5 mg) Doses can be gradually increased while remaining below standard titration levels
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