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By targeting the NNMT enzyme, it may help enhance cellular energy, promote fat utilization, and support lean muscle retention
The interest traces to a 2014 Nature paper showing that knocking down NNMT in fat and liver protected mice against diet-induced obesity, glucose intolerance, and fatty liver, partly by shifting adipose NAD+ and SAM levels [4]
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Metabolic and energy changes are gradual and depend on training, nutrition, and consistency
Peer-reviewed and received in revised form 11 January 2022
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