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We moved to once-daily liraglutide, and then to the once-weekly heavyweights: dulaglutide, semaglutide (Ozempic and Wegovy), and the dual GIP and GLP-1 agonist tirzepatide (Mounjaro and Zepbound)
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Common side effects include high blood pressure, palpitations, and insomnia, and they share similar drug interactions and contraindications, including risks when combined with MAOIs or alcohol
When administered through an IV you bypass the GI tract and get a full dose of glutathione into the bloodstream, making it more effective quicker
They found that people taking GLP-1 drugs developed dementia 40-70% less often than people taking other diabetes medicines
![Cardiovascular disease continuum-GLP-1 action. Adapted from [46]](https://www.researchgate.net/publication/357072789/figure/fig1/AS:1146405179654167@1650335702879/Cardiovascular-disease-continuum-GLP-1-action-Adapted-from-46.png)
