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Data accumulated from animal experiments conducted in acute ischemic stroke models with and without diabetes have also demonstrated a dose-dependent reduction of infarct volume in the brain by GLP-1RAs, when administered before or during the acute phase of ischemia at reperfusion or with some delay after the onset of reperfusion [60,61,62, 70]

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The choice between pre-formulated blend GHK-Cu administration and custom independent GHK-Cu dosage depends on the research question

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It activates the receptors directly