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IRE1 inhibition with KIRA6 or 48C reduces ER stress, neuronal death, and tau aggregation in PD, ALS, and AD models

Regulation of synaptic efficacy by coincidence of postsynaptic APs and EPSPs

Epidermal Cell Turnover Retinoids are natural and synthetic vitamin A derivatives that modulate cellular differentiation and proliferation through the binding to nuclear retinoic acid receptors but also through the activation of kinase signaling pathways [142]

1 These potential benefits are derived from various scientific studies and anecdotal experiences

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Maintenance Therapy : For ongoing maintenance, a monthly injection of 1 mg (1000 g) is generally sufficient to maintain adequate vitamin B12 levels in most adults