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Management of hyperglycemia associated with pasireotide (SOM230): healthy volunteer study
In the SURPASS-2 trial, patients with obesity and T2D who received tirzeapatide (5 mg weekly) achieved greater HbA1c and body weight reductions than those receiving semaglutide (1 mg weekly) during the 40 week study (64) despite comparable putative GLP-1R occupancy at these doses (47)
Due to its potent effects on glucose homeostasis and appetite regulation, GLP-1R agonists are treatments for type 2 diabetes and obesity [2, 3]
Regular monitoring and medical supervision are essential to mitigate these risks
Pregnant or nursing individuals, those taking medication, or having any medical condition should consult their doctor before taking any food supplement
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