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When patients hit a plateau at the highest dose, Azagury said that the options are to switch to a more potent drug or consider surgery
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Of note, although inhibition of PPAR diminished the glucose-lowering effect of GLP-1GIPLani, antagonization of PPAR did not ameliorate weight loss induced by either GLP-1GIPLani or the selective PPAR agonist GW501516 (Fig
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