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Molecular Metabolism , 30, 72130
The 4 mg to 8 mg jump is the hardest the GLP-1 and glucagon arms climb fastest there, while the GIP brake is already maxed out and adds nothing more
Compared to other antidiabetic medications, including metformin, sulfonylurea, thiazolidinediones (TZDs), dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT-2) inhibitors, and insulins, GLP-1-RAs boast a combination of high efficacy in glycemic control, desirable function of weight loss, low risk of hypoglycemia, and even a mild benefit on the cardiovascular system
The hydration is next level and my under-eyes look instantly plumper and smoother
GLP-1 RAs also have potential benefits in patients with various neurological diseases independent of their glucose-modulating effect
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