Their immune systems respond differently
Effects of propofol, a sedative-hypnotic drug, on the lipid profile, antioxidant indices, and cardiovascular marker enzymes in wistar rats
It's a relatively high amount for a supplement to have, but it shouldn't be a problem for most people since the maximum per-day allowance for adults is 400mcg.34 That said, you may want to avoid Doctor's Best Glutathione + Milk Thistle if you take another supplement that includes selenium or eat a lot of selenium-rich foods (e.g., Brazil nuts, tuna)
People usually think they are milder, yet they can still cause problems: 1
Test for candida or dysbiosis if GI symptoms persist
Instead of masking symptoms, it addresses the root cause of hormonal imbalance