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This is most likely with structured low-calorie programmes, bariatric surgery, or sustained intensive lifestyle change

When these plaques eventually rupture and break off, they cause clogs that block blood flow and cause heart attacks or strokes

Joint stress decreases, sleep apnea severity often improves, and inflammation markers typically fall as fat mass decreases

patients with hypertriglyceridaemia (very high triglycerides) may have an elevated baseline risk Gallbladder disease : GLP-1 receptor agonists are associated with increased risk of gallstones and cholecystitis

Fluctuations in blood glucose levels are a common trigger for headaches

Beyond the shift in hunger, users may also experience nausea or food aversion, further limiting nutritional intake