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Other Things That Can Lead to Diarrhea While Using Zepbound Not every instance of diarrhea comes from the medication
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DG-75 and BL-2 cell lines were incubated with viral particles in culture medium with 8 g/ml protamine sulfate during 16 h
Patients experiencing these symptoms while taking tirzepatide should discontinue the medication and seek immediate medical attention
For semaglutide specifically, a 2025 preformulation study tested stability at 5C, 25C, 40C, 60C, and 80C and documented accelerated degradation at higher temperatures, supporting the practice of minimizing heat exposure and refrigerating whenever possible