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While a formal ethics committee review and documentation were not conducted, the research was carried out in accordance with ethical principles aimed at protecting participant rights and ensuring privacy
While its oxidised form has a pro-oxidant effect, its reduced form (GSH or L-glutathione) constitutes a first line defence for cells (2)
Ahmed et al
Main concerns shift to nutritional deficiencies and maintaining muscle mass
However, increased growth hormone activity may carry risks such as: insulin resistance fluid retention and joint swelling cardiovascular complications abnormal tissue growth Human orthopaedic evidence remains limited, and most musculoskeletal data are still preclinical
Pipeline (Phase 3 trials completed, FDA decision pending as of April 2026): Survodutide (BI 456906): Dual GLP-1/glucagon agonist from Boehringer Ingelheim
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