Full body composition and recovery benefits develop over 36 months
Think of it as refilling a completely empty tankit takes a concentrated effort at first to get things running smoothly again
This allows the companies that produce them to set high prices without competition
Heart Health Benefits GLP-1 medications offer impressive benefits for heart health: They lower the risk of heart attacks, strokes, and cardiovascular death They help reduce blood pressure They improve blood fat levels (like cholesterol and triglycerides) They reduce inflammation that can damage blood vessels A 2024 study using statistical modeling to compare different diabetes medications found that GLP-1 medications came out on top for reducing the risk of major heart-related events and overall death risk
That matters because blood-sugar control does the opposite: HbA1c is nearly maxed out by 10 mg, so the top dose is justified by weight, not by additional glucose lowering. Body size also shifts the felt dose
In a cohort of 7 patients with DT2 and obesity, daily use of liraglutide 1.2mg achieved, after 10 weeks, a weight reduction of 5% and a decrease in BMI of 2kg/m2.80 In another study, 3 patients with DT2 and obesity achieved a decrease in BMI of between 0.8 and 3.8kg/m2 after 18 weeks with this same dose of liraglutide.81 Another 2 patients with obesity and DT2 achieved weight losses of more than 5kg and a decrease in BMI of 1.5 and 2kg/m2 after 6 weeks of treatment.82 Finally, in a series of 20 subjects with obesity and DT2, an average weight loss of 4.7kg was reported after 8 weeks of treatment with liraglutide 1.8mg.83 In most of these patients, improvements in the psoriasis area severity index (PASI) was observed, and on occasions, a decrease in psoriatic plaques