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Adverse effect profile : The most commonly reported side effects were gastrointestinal in nature including nausea, vomiting, diarrhoea, and constipation consistent with the known class effects of GLP-1 receptor agonists

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It is approved in more than 45 countries, including Austria, Germany, Russia, China, and South Korea for conditions including stroke, traumatic brain injury, and dementia

PMID: 24993939

Circadian Rhythm Sleep-Wake Disorders are a set of clinical conditions to which melatonin are classically indicated

The gut houses about 80% of the immune system