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The efficacy of RYBELSUS was not impacted by baseline age, sex, race, ethnicity, BMI, body weight, duration of diabetes and degree of renal impairment

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Simple timing framework Baseline Discuss baseline labs before starting, especially with diabetes, kidney disease, gallbladder history, pancreatitis history, liver disease, or cardiovascular concerns

This is especially important in reproductive tissues, where oxidative stress can interfere with ovulation, sperm development, or embryo implantation

The medication is doing significant work

Dehydration worsens nausea independently of the drug