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At lower titration doses, nausea rates are closer to 20%
Safety Profile: Semaglutide Side Effects and Adverse Events Semaglutide's safety record comes from multiple large-scale clinical trials involving over 10,000 participants
NGT, normal glucose tolerance
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Key takeaway Both medicines can support significant weight loss, especially at the higher, weight-management doses (Wegovy for semaglutide and Zepbound for tirzepatide)
Phase 2 trial data published in the New England Journal of Medicine showed an average of 24.2% body weight reduction at the highest research quantities over 48 weeks
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