Impact on NAION A paper published in 2024 in JAMA Ophthalmology created shock waves in the ophthalmic community by showing that subcutaneous semaglutide was associated with a significantly higher risk of developing nonarteritic anterior ischemic optic neuropathy (NAION)
Yet, despite the relatively small scale of the study, donor sexes were equally accounted for as relevant biological variables, with an observed minimal impact (especially on carnitine metabolism) compared to that of storage temperatures and additives in this pilot analysis
Yes, Ozempic can be used for long-term weight management
Emerging therapies, including nanotechnology-based drug delivery, are promising for reversing long-term neuronal damage (Nguyen et al., 2021)
[26] showed that liraglutide-dependent weight loss relies on its binding to GLP-1Rs located mainly in POMC/CART (cocaine- and amphetamine-regulated transcript) anorexigenic neurons in the ARC, but an indirect inhibitory effect of agouti-related peptide (AgRP) orexigenic neurons via -aminobutyric acid (GABA)-ergic signaling was also observed
States We Serve How we reviewed this article: GoodRx (2023)