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2020;10(9):e038071
carnitineTMAO Abstract Recent studies have implicated trimethylamine N -oxide (TMAO) in atherosclerosis, raising concern about l-carnitine, a common supplement for patients with inborn errors of metabolism (IEMs) and a TMAO precursor metabolized, in part, by intestinal microbes
Picard M, Juster RP, McEwen BS
It increases muscle protein synthesis, reduces protein breakdown, supports glucose and amino acid uptake, and suppresses programmed cell death
Carnitine acetyltransferase: a review of its biology, enzymology, and bioorganic chemistry
Like most side effects of weight-loss medications, it may pass with time, but it can be a sign of more significant issues such as kidney complications
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