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They change gastric emptying rate and transit time, which modifies the intestinal environment including local pH levels and nutrient availability
It does not establish that cagrilintides longer half-life means a better outcome half-life is pharmacokinetics, not efficacy
But in some circumstances, where they have been trialled, theyre just not showing the kind of benefits that we would need to make them effective enough to bring them to market through the NHS. Taylor says that using these unregulated peptides carries serious risks
However, they also affect how the digestive system works
Conte F, Malloggi S, De Rosa O, et al