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DPP-IV is also responsible for the regulation of macrophage/dendric cell-mediated adipose tissue inflammation (Zhong et al
Kim HS, Yoon T, Jung CH, Park JY, Lee WJ
2014;14:e15765
Activation of the GLP-1 receptor leads to inhibition of gastric emptying and small bowel motility leading to a slower absorption of nutrients
This suppression occurs just at or above fasting glucose levels, hence preserving counterregulatory responses to hypoglycaemia (Holst 2007)
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