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Common drugs that interact with grapefruit Examples of some of the most common grapefruit or grapefruit juice drug interactions that can occur include: aliskiren (Tekturna) - also apple juice, orange juice alprazolam (Xanax) amiodarone (Pacerone) atogepant (Qulipta) atorvastatin (Lipitor) budesonide (Entocort EC, Ortikos, Tarpeyo, Uceris) buspirone (Buspar) carbamazepine (Tegretol) cilostazol (Pletal) clarithromycin (Biaxin) cyclosporine (Gengraf, Neoral, Sandimmune) colchicine dronedarone (Multaq) erythromycin (E.E.S., Eryped) felodipine (Plendil) fentanyl fentanyl transdermal system (Duragesic Skin Patch) fexofenadine (Allegra) - also apple juice, orange juice flibanserin (Addyi) indinavir (Crixivan) loratadine (Claritin) losartan (Cozaar) lovastatin nilotinib (Tasigna) naloxegol (Movantik) nifedipine (Procardia, Procardia XL) palbociclib (Ibrance) pazopanib (Votrient) pimozide (Orap) ranolazine (Ranexa) rimegepant (Nurtec ODT) saquinavir (Invirase, Fortovase) sildenafil (Revatio, Viagra) simvastatin (Zocor) suzetrigine (Journavx) tadalafil (Adcirca, Cialis) ubrogepant (Ubrelvy) vardenafil (Levitra, Staxyn) verapamil (Calan, Calan SR) warfarin (cranberry juice, mangos, grapefruit seed extract, or pomegranate juice may also interact) Other resources There are numerous other drug interactions with grapefruit and grapefruit juice