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You may also get other side effects like nausea or constipation, according to StatPearls

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Tirzepatide vs semaglutide 2.4 mg in non-diabetic obesity SURMOUNT-5 direct head-to-head, -20.2% vs -13.7% at 72 weeks: Aronne NEJM 2025

Some worry about the potential for this overstimulation to trigger cancer down the road