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GLP-1 medications, such as semaglutide in Ozempic/Wegovy and the newer GLP/GIP medication tirzepatide (Mounjaro/Zepbound), were originally developed to lower blood glucose in patients with type 2 diabetes
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Tirzepatide carries a boxed warning about thyroid C-cell tumors in rodents and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2
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Boehringer Ingelheim is solely responsible for further development and global commercialization of BI 3034701
Research indicates that the combination of these peptides in laboratory settings might maximize IGF-1 and growth hormone pathway activation potentially leading to tissue development, compositional changes and overall physiological adaptations
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