A non-supplemented group served as control
However, the study had no control group and several methodological issues, so the results should be viewed with caution
Arch Gerontol Geriatr 54(2):e1e7 Trinh K, Moore K, Wes PD, Muchowski PJ, Dey J, Andrews L, Pallanck LJ (2008) Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinsons disease
To counteract C-terminal truncation-induced Syn toxicity, cells may employ compensatory mechanisms such as S129p
In type 2 diabetes [161] and sickle cell disease [162], The NLRP3 inflammasome has been reported to drive chronic low-grade inflammation by recognizing cytoplasmic mtDNA or mitochondrial ROS, recruiting the ASC adaptor protein and pro-caspase-1, and mediating IL-1/IL-18 maturation and cell death
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