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Definitions Animal experiment - a research experiment performed in a laboratory animal

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Taken together, preclinical and clinical studies have demonstrated that GLP-1 receptor agonists exert pleiotropic effects extending beyond glycemic control, influencing multiple organ systems including the nervous, respiratory, hepatic, renal, cardiovascular, reproductive, and immune systems (Figure 4)

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A 2025 study of high dose semaglutide injection (7.2 mg) showed that adults with obesity lost around 21% of their body weight after 72 weeks