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A Phase 2a randomised trial published in Nature Medicine (2024) found that Retatrutide produced an 81.4% (8mg) and 82.4% (12mg) relative reduction in liver fat at 24 weeks, the most significant hepatic fat reduction recorded for a peptide of this class
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Like Trulicity, Mounjaro is a once-weekly injection approved for type 2 diabetes and has similar ways of working
Below, every draw volume is computed from a 5 mg vial reconstituted with 2 mL of bacteriostatic water (2.5 mg/mL) the most common starting configuration with 10 mg equivalents shown for comparison
Dr Blauvelt: I actually have been going around recently lecturing on psoriasis and talking about these studies, and one of the things that always comes up is: Should I, as a dermatology practitionerwhether its a dermatologist, a PA [physician assistant], or NP [nurse practitioner],should I be the one prescribing GLP-1s to my patients? Its pretty controversial and its pretty interesting