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Prodromal symptoms were reported by 56.1% of patients prior to attacks, being most frequent erythema marginatum (38.7% of patients), and 84.7% could identify an attack trigger: 66.9% cited stress, 56.2% trauma, 36.2% infections, 27.5% menstruation, 15.6% pregnancy, 9.4% exogenous oestrogens, and 22.5% other factors
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doi: 10.2337/db16-1343 36 WatkinsRAEvans-MolinaCTerrellJKDayKHGuindonLRestrepoIAet al
Variants in MC4R gene (rs17782313) affect appetite regulation and glucose sensitivitythe exact same pathways both medications target
While rare cases of idiosyncratic drug-induced liver injury have been reported, there is no established direct link between GLP-1 receptor agonists and serious hepatotoxicity in patients with normal baseline liver function
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