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In contrast to LDL, high-density lipoprotein (HDL) inhibits the expression of surface markers and inflammation-related genes such as TNF-, IL-6, and monocyte chemotactic protein-1 (MCP-1) in macrophages, reducing the production of ROS and RNS and blocking the polarization of macrophages toward the M1 type (175)
Uninsured patients who invest in genetic testing early avoid months of trial-and-error dosing, ultimately reducing total medication costs through precision selection
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