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The vascular endothelial dysfunction is a critical step of atherogenesis which is usually characterized by endothelium-dependent vasodilatation and vasoconstriction imbalance and the disturbed balance of antithrombotic and prothrombotic factors 4
Its essential for energy metabolism and neurological function, but it's also notoriously fragile
For GLP-1 users, this creates perfect metabolic synergy
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