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doi: 10.1002/dmrr.3353 12 VermaSMcMurrayJJV
It is plausible that excessive ROS from other metabolic disorders (such as obesity, insulin resistance, and elevated LDL-cholesterol and low HDL-cholesterol) can induce a state of chronic low-grade inflammation (e.g., raising IFN- and TNF-), possibly aggravating or activating vitiligo in genetically predisposed individuals, as illustrated in Figure 1
Current Pharmaceutical Design Chang CH et al
Q2- Are injections of methylcobalamin superior to oral vitamin B12 supplements
Furthermore, SSTRs, particularly SSTR5, are highly expressed in intestinal L-cells that secrete glucagon-like peptide-1 (GLP-1) and K-cells that secrete glucose-dependent insulinotropic polypeptide (GIP)