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Gangwar, A., et al

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This change eliminates the estimated prior cost of around $34 per patient, making it more accessible for those who need it

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Where It Acts The primary target cells are dermal fibroblasts (the cells responsible for producing collagen, elastin, and the extracellular matrix proteins that give skin its mechanical structure) and basal keratinocytes (the proliferating cell population at the bottom of the epidermis)

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Targeting signaling pathways NF-B signaling pathway Persistent NF-B activation drives the SASP 267

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