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PBMs employ a range of coverage strategies to manage the use of GLP-1s for weight loss, tailored to the needs and goals of their clients

High-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer cases

However, further research is needed to determine which groups may benefit most from this treatment

For instance, limiting coverage to those with higher BMI levels could mean forfeiting rebates and increasing cost per person treated

However, these patients had multiple risk factors for b12 deficiency beyond semaglutide use, including previous gastric surgery that permanently alters stomach anatomy and reduces intrinsic factor production

In addition, studies have found that compared with placebo, semaglutide significantly reduced AF incidence by 42% in high-cardiovascular-risk populations, and this effect was independent of administration route (oral/subcutaneous/injection), presence of underlying diabetes, and BMI (125, 127)