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For the analysis of lipids in the serum from WT, Gclc L-KO, Nrf2 L-KO, and L-DKO mice, the methods were the same with the following exceptions: MS2 scan conditions were applied in positive mode, the scan range was from m/z 120-1000, and the resolution was 120,000 for MS

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Triglycerides tend to decrease while HDL cholesterol may increase, particularly when weight loss is substantial