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Stress can also shift the gut microbiome

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[48] However, the genes that have mutated in these diseases all have roles in the repair of DNA damage and the increased DNA damage may, itself, be a factor in the premature aging (see DNA damage theory of aging)

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Unknown Important limits No established long-term human safety data exists

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R., Nielsen, D

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Simeon 2000 Life Sci simultaneously documented the stimulation of matrix repair and the suppression of degradation by MMP-2 and MMP-9 (matrix metalloproteases), a unique profile of constructive rather than destructive remodelling

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