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The most common side effects for both injectable and oral forms of semaglutide (Wegovy) include gut issues, such as nausea, vomiting, diarrhea, and constipation, said Hamlet Gasoyan, PhD, assistant professor of medicine at Cleveland Clinic Lerner College of Medicine

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Key Takeaways Dual mechanism: Empagliflozin helps remove glucose through urine, while metformin lowers liver glucose output