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REFERENCES Centers for Disease Control and Prevention
Importantly, these increases did not correlate with serious adverse cardiovascular events in the trial populations, and heart rate typically returned toward baseline levels as treatment continued beyond the dose-escalation phase
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Additionally, NAD + is required for fatty acid metabolism during -oxidation, glutaminolysis generating -ketoglutarate, mitochondrial shuttling of metabolites, and lactic acid fermentation 3,4,5
Fatty liver disease is when fat builds up in your liver
However, phase 2 trials are not powered to detect rare cardiovascular events
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