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PMID: 21218090

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While it is not known if the impact on blood pressure was due to the medication or the participants weight loss, the lower blood pressure measures seen with tirzepatide rivaled what is seen for many hypertension medications. The current research was a planned sub-study including 600 of the participants from the SURMOUNT-1 weight loss study to determine if there was an effect on blood pressure

Only the brand-name versions manufactured by Novo Nordisk (Ozempic, Wegovy, and Rybelsus) have received FDA approval

The highest dose led to 23.7% average weight loss at 68 weeks when including all participants and 28.7% among those who completed treatment