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Modifying the hormone GLP-1 encourages the body to release insulin and signals the brain to feel more full
GLP-1 receptor agonists mimic a hormone called glucagon-like peptide-1 (GLP-1)
Peanut butter
They mimic the action of endogenous GLP-1, a hormone naturally released by cells in the small intestine in response to food intake and exert effects 16 (Figure 1) in a dose-dependent manner 17
It can be administered at any time of day, with or without meals
Prolonged cAMP signaling and homologous desensitization Intuitively, reduced loss of surface GLP-1R with exendin-phe1 should permit greater access to extracellular ligand during continuous exposure, with fast recycling ensuring that the receptors are maintained in a sensitized state
