Among the identified sites, H3K18la is the best characterized, promoting the transcription of tissue-repair and anti-inflammatory genes such as Arg1 during M1-to-M2 macrophage polarization [15, 84]
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Moreover, H 2 O 2 , one of the most studied reactive oxygen species in plants, did not induce any detectable reduction of PMA at the tested concentrations, reinforcing the selectivity of the method toward biological reductants rather than general oxidants
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