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Maintaining muscle mass is crucial for metabolic health, as skeletal muscle is a major site of glucose disposal and insulin action

This leads to increased production of antioxidant enzymes such as superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT)

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Haire-Joshu D, Tabak R

Cells were seeded in 24-well plates and transfected 24 h later using Lipofectamine 3000 with 100 ng of the reporter construct or an empty vector (GV308) as a negative control