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[17] [18] Additional risk factors include: Female sex and pregnancy history : Women, particularly those who have been pregnant, have higher baseline gallstone risk Age over 40 years : Gallbladder disease incidence increases with age Obesity : Higher BMI correlates with increased gallstone prevalence Diabetes : Type 2 diabetes itself is associated with gallbladder dysfunction Rapid weight cycling : History of repeated weight loss and regain Certain ethnicities : Native American and Hispanic populations have higher gallstone rates [23] [24] Family history : Genetic predisposition to gallbladder disease Estrogen therapy : May increase cholesterol saturation in bile Patients with multiple risk factors should engage in thorough discussion with their healthcare provider about symptom awareness

Brain and Behavior , 15 (7), e70661

it must be taken on the same day each week, but it can be injected at any time of day, with or without food

10.1038/s41598-024-80829-w 123 MaheshvareM

8 This extensive expression of the GLP-1 receptor explains the wide-ranging effects of GLP-1 drugs

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