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A formal Phase 2 trial was completed in 2009, but over 15 years later, the results have never been published, another major red flag suggesting it failed to prove effective or safe

They are integral to various biological processes, from hormone production to cell signaling

When applied around a herniated disc, TB-500 appears to help seal tears in the outer annulus, preventing further disc material from leaking out

Studies documented growth factor upregulation and cellular migration patterns to injury sites

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