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In a recent Cochrane review, it was stated that the chance of live birth with ICSI is between 30% and 41% (223)

Presented for research literature review only Sugimoto M et al

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As the authors point out, long-term proton pump inhibitor use is connected to serious side effects and increases the risk of some other potentially serious conditions such as Clostridium difficile associated diarrhea, osteoporosis, and vitamin or electrolyte malabsorption

Propionic acidemia: identification of twenty-four novel mutations in Europe and North America

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