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Active site residues C46, A48, Q81, and W136 are highlighted and shown as sticks

Avoid repeated temperature fluctuations

Very high doses of vitamin C injections also seem to have few side effects

Oxid Med Cell Longev 2021:8852759 Dixon D, Edmonds M (2021) Managing diabetic foot ulcers: pharmacotherapy for wound healing

But the compound, given twice weekly, did not help those people whose symptoms were evident for between one and three years, and no one showed significant benefits