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Exenatide is contraindicated in patients with severe renal impairment (eGFR/CrCl below 30 mL/min), and lixisenatide is not recommended in severe renal impairment (eGFR below 15 mL/min)
Case series, such as that described by Lotz-Havla et al
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Instead, they suppress appetite so effectively that users simply eat less food, and therefore consume fewer nutrients
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