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450 Personalized treatment leverages comprehensive profiling of tumor genomics, mutational landscapes, immune status, and evolutionary trajectories to tailor therapy selection and minimize resistance

Women account for nearly 90% of diagnosed IC/BPS cases, making coordinated, patient-centered care essential for effective long-term symptom management

Studies in mice have shown that peroxiredoxin-4 can be used to protect against ovarian ageing (179, 180)

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We also tested the ability of -glutamylcysteine to induce protein modification, which was found to be well below that of GSH (Supplementary Table S3)