These are structural relationships and carry no implication about comparative activity or relative usefulness
16 GLP-1RAs achieve sustained pharmacological effects by resisting degradation by DPP-4 in the body, consequently contributing to hyperglycemia and insulin resistance related to glucose metabolism, 17,18 lipid profile alterations, changes in fat composition, visceral fat accumulation, and obesity related to lipid metabolism, 1921 which constitute the systemic metabolic characteristics of interest in MASLD management
The most common drug-induced causes are: 1Diuretics loop diuretics (e.g
Diabetology International, 13 ,
10.4070/kcj.2023.0048 Korean Circ J
This process can compromise physical performance, slow down metabolism, and reduce overall resilience