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Individuals suffering from B12 vitamin deficiency will be able to reestablish appropriate sleep patterns and, as a result, will be able to live healthier lives

For instance, in the PDAPP (J9) mouse model of AD, metformin treatment improved memory function in female mice but worsened it in males, highlighting the importance of sex-specific considerations in evaluating its cognitive effect 59

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Knowing the patient profile that benefits most from this medication, and understanding the contraindications, is part of responsible, medically supervised prescribing