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Bibcode:2004PNAS..101.4222B
Based on Phase 2 trial data, nausea associated with retatrutide is most common during the early weeks of treatment or following each dose increase, and typically diminishes over time as the body adjusts to the medication
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It can cause a "fishy" odor of the urine, breath, and sweat
Hum Genet Genomics Adv 4:100150
The body adjusts during a break, and restarting at the previous dose without re-titration leads to a strong return of GI side effects
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